Names
X
Name
Species
Main
PRP4 
Homo sapiens, Mus musculus 
False 
PRP4K 
Homo sapiens, Mus musculus 
True 
PRPK 
 
False 
Prpf4b 
mus 
false 
Keywords
X
chromatin associated, cotranscriptional splicing, deacetylase complex, gene trap, kinase, Kinase Domain, kinetochore, nuclear mRNA splicing via spliceosome, regulation of transcription DNA_dependent, RS Domain, snRNP associated, splicing speckles, SR_RS domain, U5 snRNP
Location
X
Location
Species
6p24-25 
Homo sapiens 
13A5 
Mus musculus 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
diffuse/speckles 
Diffuse and speckle associated; colocalises with Pinin, PRP6, SWAP, SC35 
PubMed:12077342
Mitosis 
chromatin 
Minority PRP4K remains associated with mitotic chromosomes 
PubMed:12077342
Mitosis 
kinetochore 
 
pubmed:17998396
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
116.83 
10.24 
152 
 
1007 
Entrez Protein:AAH03769
Entrez Protein:AAM19102
Uniprot:Q61136
116.97 
10.26 
152 
 
1007 
Entrez Protein:XP_004079
Entrez Protein:AAM19101
Uniprot:Q96QT7
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0000398 
nuclear mRNA splicing, via spliceosome 
PubMed:12077342
PubMed:15452250
PubMed:9102632
GO:0006355 
regulation of transcription, DNA-dependent 
PubMed:12077342
GO:0031577 
spindle checkpoint 
pubmed:17998396
Molecular Function
X
GO ID
Term
Links
GO:0004712 
protein threonine/tyrosine kinase activity 
PubMed:12077342
PubMed:9102632
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
In situ 
High expression in cerebellum, hippocampus and olfactory bulb of the brain 
PubMed:11418604
Northern 
Ubiquitous 
PubMed:10799319
PubMed:11418604
Related Genes
X
Name
Species
Links
hPRP4 
Homo sapiens 
PubMed:11418604
PubMed:9102632
mPRP4 
Mus musculus 
PubMed:9102632
PRP4 
Schizosaccharomyces pombe 
PubMed:8371982
F22D6.5 
Caenorhabditis elegans 
Entrez Protein:NP_492008
GH04978 
Drosophila melanogaster 
Entrez Protein:NP_612010
CAB67671 
Arabidopsis 
Entrez Protein:CAB67671
History
X
Created On
Last Changed
2000-10-24 13:04:03 
2004-12-02 15:09:52