Names
Name
Species
Main
PRP4 
Homo sapiens, Mus musculus 
False 
PRP4K 
Homo sapiens, Mus musculus 
True 
PRPK 
 
False 
Prpf4b 
mus 
false 
Keywords
chromatin associated, cotranscriptional splicing, deacetylase complex, gene trap, kinase, Kinase Domain, kinetochore, nuclear mRNA splicing via spliceosome, regulation of transcription DNA_dependent, RS Domain, snRNP associated, splicing speckles, SR_RS domain, U5 snRNP
Location
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
diffuse/speckles 
Diffuse and speckle associated; colocalises with Pinin, PRP6, SWAP, SC35 
Mitosis 
chromatin 
Minority PRP4K remains associated with mitotic chromosomes 
Mitosis 
kinetochore 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
47 
80 
KKHK box 
lysine/histidine repeat (4 X ) 
56 
73 
NLS BP 
 
68 
85 
NLS BP 
 
160 
578 
SR/RS 
large RS/SR domain similar to SRp75 
275 
292 
NLS BP 
 
290 
307 
NLS BP 
 
351 
368 
NLS BP 
 
401 
418 
NLS BP 
 
448 
465 
NLS BP 
 
456 
473 
NLS BP 
 
462 
479 
NLS BP 
 
470 
487 
NLS BP 
 
482 
499 
NLS BP 
 
687 
1003 
STYKc 
dual specificity kinase domain ( ser_thr_tyr ) 
Biological Process
GO ID
Term
Links
GO:0000398 
nuclear mRNA splicing, via spliceosome 
GO:0006355 
regulation of transcription, DNA-dependent 
GO:0031577 
spindle checkpoint 
Molecular Function
GO ID
Term
Links
GO:0004712 
protein threonine/tyrosine kinase activity 
Other Function
Function
Links
Expression
Experiment
Detail
Links
In situ 
High expression in cerebellum, hippocampus and olfactory bulb of the brain 
Northern 
Ubiquitous 
Related Genes
Name
Species
Links
hPRP4 
Homo sapiens 
mPRP4 
Mus musculus 
PRP4 
Schizosaccharomyces pombe 
F22D6.5 
Caenorhabditis elegans 
GH04978 
Drosophila melanogaster 
CAB67671 
Arabidopsis 
History
Created On
Last Changed
2000-10-24 13:04:03 
2004-12-02 15:09:52