Names
X
Name
Species
Main
ES446 
Mus musculus 
True 
HMGA2 
Homo sapiens 
False 
HmgI-C 
Homo sapiens, Mus musculus 
False 
pygmy locus 
Mus musculus 
False 
Keywords
X
cancer-associated translocations, cancer, chromatin associated, gene trap, high mobility group protein, mitotic chromosomes, obesity, pygmy, AT-hook, growth, EMT, stem cell, genetic disease
Location
X
Location
Species
10 
Mus musculus 
12q15 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
chromatin 
 
PubMed:11555636
Mitosis 
heterochromatin 
 
PubMed:11555636
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
11.8 
10.63 
 
 
108 
PubMed:10747931
PubMed:11555636
PubMed:8918814
PubMed:9614921
PubMed:7651535
Entrez Nucleotide:X58380
Uniprot:P52927
PubMed:17045619
PubMed:20576167
11.8 
10.63 
 
 
109 
PubMed:10472377
OMIM:600698
Entrez Nucleotide:NM_003483
Uniprot:P52926
Annotation
X
Start
End
Domain
Description
24 
51 
NLS BP 
 
26 
38 
AT hook 
 
46 
58 
AT hook 
 
66 
82 
NLS BP 
 
74 
86 
AT hook 
 
1 
84 
gene trap insertion 
same intron as human translocation breakpoints 
1 
108 
full length 
 
24 
49 
NLS BP 
 
26 
35 
AT hook 
 
44 
55 
AT hook 
 
66 
82 
NLS BP 
 
74 
82 
AT hook 
 
95 
108 
acidic domain 
 
Biological Process
X
GO ID
Term
Links
GO:0040007 
growth 
pubmed:17767157
GOIDHERE 
epithelial to mesenchymal transition 
pubmed:16831886
pubmed: 18832382
GO:0055006 
cardiac cell development 
pubmed:18425117
GO:0019827 
stem cell maintenance 
Molecular Function
X
GO ID
Term
Links
GO:0003680 
AT DNA binding 
pubmed:17956125
GO:0003677 
DNA binding 
PubMed:10747931
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
In situ 
Hmgic expression correlates throughout fetal development with high proliferative activity. 
PubMed:9824208
 
induced by the Smad pathway during EMT. 
pubmed:16831886
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-01-05 15:26:34 
2001-10-01 17:38:23