Names
Name
Species
Main
All-1 
 
False 
HRX 
Homo sapiens 
False 
MLL 
Mus musculus 
False 
WF9/1D1 
 
True 
CXXC7 
 
false 
KMT2A 
 
false 
Mll1 
 
false 
Keywords
acute leukemia, acute lymphoblastic leukemia ALL, AML, bromodomain, fycn, histone methylase, homeotic gene regulation, leukaemia, leukaemia_associated translocation, lymphoma_associated translocation, mitotic chromosomes, segment identity, Trithorax group TrxG, zinc finger CXXC, set domain, AT-hook, H3K4me3 binding, H3K4 methylation, MLL1/2 complex, genetic disease, transcription activation, transcription repression, proline isomerisation, genetic disease, Wiedemann-Steiner syndrome, CdLS, FY-rich domain
Location
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
PcG bodies 
In foci with Bmi, antagonist to Bmi 
Mitosis 
chromosomal 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
 
 
 
 
 
Annotation
Start
End
Domain
Description
170 
gene trap insertion 
 
3968 
full length 
 
170 
310 
AT hook 
 
171 
177 
NLS 
 
256 
272 
NLS BP 
 
528 
544 
NLS BP 
 
602 
608 
NLS 
 
733 
738 
NLS 
 
814 
817 
NLS 
 
891 
894 
NLS 
 
1143 
1150 
NLS 
 
1149 
1194 
CXXC Zn finger 
 
1315 
1332 
NLS BP 
 
1400 
1600 
leukaemia breakpoint cluster 
 
1433 
1482 
PHD finger 
 
1481 
1531 
PHD finger 
 
1517 
1523 
NLS 
 
1568 
1627 
PHD finger 
 
1703 
1748 
Bromo 
 
1932 
1978 
PHD finger 
 
1994 
2010 
NLS BP 
 
2029 
2072 
FYRN 
 
2514 
2520 
NLS 
 
3218 
3221 
NLS 
 
3535 
3556 
NLS BP 
 
3667 
3752 
FYRC 
 
3822 
3950 
SET 
 
3952 
3968 
post SET 
 
Biological Process
GO ID
Term
Links
GO:0016571 
histone methylation 
GO:0000122 
negative regulation of transcription from Pol II promoter 
GO:0007379 
segment specification 
GO:0006344 
maintenance of chromatin silencing 
Molecular Function
GO ID
Term
Links
GO:0003677 
DNA binding 
GO:0042800 
histone lysine N-methyltransferase activity (H3-K4 specific) 
GO:0035064 
methylated histone residue binding 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
Set1 
Saccharomyces cerevisiae 
trithorax 
Drosophila melanogaster 
History
Created On
Last Changed
2001-01-05 17:37:50 
2005-08-18 13:20:36