Names
Name
Species
Main
F9/28A5 
Mus musculus 
True 
HELLS 
 
False 
LSH 
 
False 
PASG 
Homo sapiens, Mus musculus 
False 
SMARCA6 
Homo sapiens 
False 
Keywords
chromatin remodelling, chromosome instability, gene trap, helicase, histone methylation, leukaemia, meiosis, meiotic prophase, transcription repression, swi_snf, DNA methylation, polycomb complex, ds break repair, genetic disease, ICF syndrome, macroH2A, replication fork stability
Location
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
diffuse 
 
Interphase 
heterochromatin 
 
Annotation
Start
End
Domain
Description
95 
112 
NLS BP 
 
219 
411 
DEAD box 
 
226 
577 
SNF2 N term 
 
629 
712 
Helicase 
 
711 
gene trap insertion 
 
821 
full length 
 
16 
97 
coiled-coil 
 
86 
89 
NLS 
 
107 
113 
NLS 
 
136 
139 
NLS 
 
202 
394 
DEAD box 
 
209 
560 
SNF2 N term 
 
487 
494 
NLS 
 
592 
598 
NLS 
 
612 
695 
helicase C 
 
Biological Process
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
GO:0006342 
chromatin silencing 
GO:0007128 
meiotic prophase I 
GO:0000070 
mitotic sister chromatid segregation 
GO:0016564 
transcription repressor activity 
GO:0006340 
negative regulation of transcription of homeotic gene (Polycomb group) 
GO:0006302 
double-strand break repair 
GO:0048478 
replication fork protection 
Molecular Function
GO ID
Term
Links
GO:0003678 
DNA helicase activity 
GO:0043486 
histone exchange 
Other Function
Function
Links
growth retardation and premature aging 
silencing of repetitive elements 
T cell proliferation 
Expression
Experiment
Detail
Links
Immunohistochemistry 
In development highest expression in developing face, limbs, skeletal muscle, heart, and tail 
Northern 
Proliferating tissues e.g thymus, testis, bone marrow 
Related Genes
Name
Species
Links
snf2 
Saccharomyces cerevisiae 
irc5 
Saccharomyces cerevisiae 
DDM1 
Arabidopsis 
History
Created On
Last Changed
2001-01-08 12:46:35 
2007-06-20 16:44:09