Names
Keywords
gene trap, histone deacetylase complex, homeotic gene regulation, polycomb group, transcription repression, X inactivation, ubiquitination, polycomb complex, PRC2, methyl-lysine binding, genetic disease, Weaver syndrome, Cohen-Gibson syndrome, overgrowth
Location
Location
Species
Mus musculus 
11q14.2-q22.3 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
diffuse 
in complex with EZH 
Interphase 
inactive X 
with Enx1 on inactive X in trophoblast stem cells 
Mitosis 
inactive X 
with Enx1 on inactive X in trophoblast stem cells 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
15 
gene trap insertion 
 
441 
full length 
 
16 
22 
NLS 
 
81 
125 
WD40 
 
131 
176 
WD40 
 
179 
219 
WD40 
 
222 
264 
WD40 
 
295 
332 
WD40 
 
352 
390 
WD40 
 
397 
438 
WD40 
 
Biological Process
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
GO:0006342 
chromatin silencing 
GO:0016571 
histone methylation 
GO:0006349 
imprinting 
GO:0006357 
regulation of transcription from Pol II promoter 
Molecular Function
GO ID
Term
Links
GO:0003682 
chromatin binding 
GOIDHERE 
binding to H3K27me3 
GO:0080008 
CUL4 RING ubiquitin ligase complex 
Other Function
Function
Links
Gastrulation defects earlier than Hox gene expression. 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
Mes6 
Caenorhabditis elegans 
Fis3 
Arabidopsis 
Esc 
Drosophila melanogaster 
History
Created On
Last Changed
2001-01-08 13:39:53 
2005-07-21 09:34:00