Names
Keywords
acute leukemia, base excision repair, bromodomain, cancer, genetic disease, haemopoiesis, histone acetyltransferase, kix, mental retardation, acetylated histone binding, stem cell, zinc finger TAZ, zinc finger ZZ, nuclear stress body, KAT domain, Rubinstein-Taybi syndrome, leukaemia_associated translocation, ALL
Location
Location
Species
16p13.3 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
diffuse 
 
Interphase 
PML/ND10 bodies 
accumulates in PML bodies, but moves rapidly in and out cf sp100 and pml 
Interphase 
nuclear stress bodies 
after heat shock 
Annotation
Start
End
Domain
Description
10 
18 
NLS 
 
348 
354 
NLS 
 
348 
433 
TAZ Zn finger 
 
587 
667 
KIX 
methylated by CARM 
1077 
1086 
NLS 
 
1084 
1194 
Bromo 
 
1236 
1314 
PHD finger 
essential for HAT activity 
1317 
1320 
NLS 
 
1494 
1500 
NLS 
 
1591 
1608 
NLS BP 
 
1701 
1742 
Zn finger ZZ 
 
1766 
1844 
TAZ Zn finger 
 
10 
18 
NLS 
 
347 
353 
NLS 
 
347 
432 
TAZ Zn finger 
 
1078 
1087 
NLS 
 
1085 
1195 
Bromo 
 
1318 
1321 
NLS 
 
1495 
1501 
NLS 
 
1592 
1608 
NLS BP 
 
1702 
1743 
Zn finger ZZ 
 
1767 
1845 
TAZ Zn finger 
 
1317 
1620 
KAT11 
 
Biological Process
GO ID
Term
Links
GO:0006284 
base-excision repair 
GO:0006473 
protein amino acid acetylation 
GO:0006357 
regulation of transcription from Pol II promoter 
Molecular Function
GO ID
Term
Links
GO:0004402 
histone acetyltransferase activity 
GO:0003713 
transcription coactivator activity 
GO:0016563 
transcriptional activator activity 
GO:0070577 
histone acetyl-lysine binding 
GO:0032931 
histone acetyltransferase activity (H3-K56 specific) 
Other Function
Function
Links
haematopoietic stem cell renewal 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
p300 
Homo sapiens 
CBP 
Drosophila melanogaster 
History
Created On
Last Changed
2001-03-26 13:14:41 
2004-12-04 20:21:34