Names
X
Name
Species
Main
Bub1 
Homo sapiens 
True 
Keywords
X
chromosome segregation, histone phosphorylation, kinase, neocentromere, serine threonine kinase, spindle checkpoint
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
metaphase - mitosis 
kinetochore 
including neocentromeres 
PubMed:10607828
PubMed:11129339
PubMed:15561729
PubMed:9660858
prophase - mitosis 
kinetochore 
preceeds BubR1 
PubMed:9914370
prometapha 
kinetochore 
 
PubMed:15182667
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
 
 
 
 
1085 
Entrez Protein:O43683
PubMed:9521327
OMIM:602452
Uniprot:O43683
 
 
 
 
 
Entrez Protein:T30178
PubMed:97325748
Annotation
X
Start
End
Domain
Description
262 
279 
NLS 
 
787 
1073 
S_TKc 
 
Biological Process
X
GO ID
Term
Links
GO:0007093 
mitotic checkpoint 
PubMed:97325748
PubMed:9182760
GO:0000069 
centromere and kinetochore complex maturation 
PubMed:17389228
GO:0007063 
regulation of sister chromatid cohesion 
PubMed:15604152
PubMed:15723797
Molecular Function
X
GO ID
Term
Links
GO:0004674 
protein serine/threonine kinase activity 
pubmed:19965387
GO:0016572 
histone phosphorylation 
pubmed:19965387
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
Bub1 
Saccharomyces cerevisiae 
Entrez Protein:S64506
PubMed:10837255
Bub1 
Drosophila melanogaster 
PubMed:10402457
Entrez Protein:AAF57298
Bub1 
Schizosaccharomyces pombe 
Entrez Protein:CAA22865
PubMed:9864354
Bub1 
Xenopus laevis 
Entrez Protein:AAK12628
History
X
Created On
Last Changed
2001-04-10 14:07:22 
2007-07-31 12:00:20