Names
Name
Species
Main
Bub1b 
Homo sapiens, Mus musculus 
False 
BUBR1 
Homo sapiens 
True 
MAD3L 
Homo sapiens 
False 
Keywords
aneuploidy, cancer, kinase, neocentromere, serine threonine kinase, spindle checkpoint, genetic disease
Location
Location
Species
15q15 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
metaphase - mitosis 
kinetochore 
needs bub3, interacts with CenP-E. present on neocentromeres 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
438 
454 
NLS 
 
755 
1023 
S_TKc 
 
Biological Process
GO ID
Term
Links
GO:0000075 
cell cycle checkpoint 
GO:0000077 
DNA damage checkpoint 
GO:0007093 
mitotic checkpoint 
GO:0007049 
cell cycle 
GO:0001301 
progressive alteration of chromatin during cell aging 
Molecular Function
GO ID
Term
Links
GO:0004674 
protein serine/threonine kinase activity 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
Bub1 
Saccharomyces cerevisiae 
Mad3 
Saccharomyces cerevisiae 
History