Names
X
Name
Species
Main
MAD2 
 
False 
MAD2A 
Homo sapiens 
False 
MAD2L1 
Homo sapiens 
True 
Keywords
X
chromosome segregation, neocentromere, nuclear pore complex, spindle checkpoint, spindle pole
Location
X
Location
Species
4q27 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Mitosis 
kinetochore 
sequesters CDC20 to prevent activation of APC 
PubMed:10995431
Mitosis 
spindle microtubules 
 
PubMed:10995431
PubMed:15561729
Mitosis 
spindle poles 
 
PubMed:10995431
Interphase 
nuclear periphery 
 
Interphase 
nuclear pores 
 
PubMed:11181178
prometapha 
kinetochore 
staining of unattached chromosomes. Including neocentromeres 
PubMed:11181178
PubMed:10607828
anaphase - mitosis 
 
no staining 
PubMed:11181178
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
23.5 
5.02 
 
 
205 
Entrez Protein:Q13257
PubMed:11201745
PubMed:20165182
OMIM:601467
Uniprot:Q13257
 
 
 
 
205 
Entrez Protein:Q9Z1B5
PubMed:11201745
PubMed:10892650
Uniprot:Q9Z1B5
Annotation
X
Start
End
Domain
Description
12 
201 
HORMA 
 
Biological Process
X
GO ID
Term
Links
GO:0007093 
mitotic checkpoint 
PubMed:11274370
PubMed:10892650
PubMed:11201745
PubMed:15070740
PubMed:20165182
GO:0007144 
female meiosis I 
PubMed:15655110
Molecular Function
X
GO ID
Term
Links
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
MAD2 
Saccharomyces cerevisiae 
Entrez Protein:NP_012504
Uniprot:P40958
MAD2 
Schizosaccharomyces pombe 
Entrez Protein:O14417
Uniprot:O14417
History
X
Created On
Last Changed
2001-04-10 16:20:54 
2005-02-01 09:09:03