Names
X
Name
Species
Main
HREV7 
Homo sapiens 
False 
MAD2B 
Homo sapiens, Mus musculus 
False 
MAD2L2 
Homo sapiens, Mus musculus 
True 
REV7 
 
false 
Keywords
X
primordial germ cells, mitotic checkpoint, H3K9 demethylation, nhej, H3K27 methylation, dna damage response, chromosome segregation, ds break repair, DNA repair, shieldin complex
Location
+
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
24.3 
6.05 
 
 
211 
Entrez Protein:NP_006332
OMIM:604094
Uniprot:Q9UI95
Annotation
X
Start
End
Domain
Description
44 
47 
NLS 
 
Biological Process
X
GO ID
Term
Links
GO:0007093 
mitotic checkpoint 
pubmed: 24100295
GO:1902099 
regulation of metaphase/anaphase transition of cell cycle 
pubmed: 24100295
GO:0007281 
germ cell development 
pubmed:24009519
pubmed:23463509
GO:0031060 
regulation of histone methylation 
pubmed:24009519
pubmed:23463509
GOIDHERE 
DNA damage response, detection of DNA damage 
pubmed:23463509
GO:0007059 
chromosome segregation 
pubmed:23303771
GO:0006303 
double-strand break repair via nonhomologous end joining 
pubmed:29160738
pubmed:30046110
GO:0006302 
double-strand break repair 
pubmed:29789392
Molecular Function
X
GO ID
Term
Links
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
 
rapidly degraded at anaphase 
pubmed: 24100295
 
highly expressed in testis 
pubmed:23463509
 
expression confined to germ cells after birth 
pubmed:23463509
Related Genes
X
Name
Species
Links
MAD2 
Saccharomyces cerevisiae 
History
X
Created On
Last Changed
2001-04-10 16:42:09 
2001-09-05 10:14:44