Names
X
Name
Species
Main
hCAP-E 
Homo sapiens, Mus musculus 
True 
ScII 
Gallus gallus 
False 
SMC2 
Homo sapiens 
False 
XCAP-E 
Xenopus laevis 
False 
Keywords
X
ATPase, chromosome scaffold, condensin, heterodimer, histone phosphorylation, mitotic chromosomes, SMC
Location
X
Location
Species
9 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
cytoplasmic 
 
PubMed:10958694
Mitosis 
chromosomal 
colocalisation with phosphorylated H3 
PubMed:10958694
PubMed:15609038
prophase - mitosis 
chromosomal 
colocalisation with phosphorylated H3 
PubMed:10958694
Interphase 
nucleolus 
 
PubMed:11694586
PubMed:15635413
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
135.8 
8.68 
 
 
1197 
Entrez Protein:NP_006435
OMIM:605576
PubMed Central:9789013
Uniprot:O95347
 
 
 
 
1203 
Entrez Protein:P50533
 
 
 
 
1189 
Entrez Protein:Q90988
 
 
 
 
1191 
Entrez Protein:Q8CG48
Annotation
X
Start
End
Domain
Description
1 
171 
SMC N term 
 
32 
39 
ATP_GTP binding site motif A 
 
272 
288 
NLS BP 
 
919 
922 
NLS 
 
968 
1173 
SMC C term 
 
1003 
1006 
NLS 
 
Biological Process
X
GO ID
Term
Links
GO:0007076 
mitotic chromosome condensation 
PubMed Central:9789013
PubMed Central:16998479
GO:0030261 
chromosome condensation 
PubMed:11136719
PubMed:12919682
PubMed:16998479
Molecular Function
X
GO ID
Term
Links
GO:0004002 
ATPase activity 
Other Function
X
Function
Links
Expression
+
Related Genes
X
Name
Species
Links
SMC2 
Saccharomyces cerevisiae 
Entrez Protein:NP_116687
Cut14 
Schizosaccharomyces pombe 
Entrez Protein:CAB83164
MIX-1 
Caenorhabditis elegans 
Entrez Protein:NP_496331
History
X
Created On
Last Changed
2001-04-11 12:02:55 
2004-12-02 15:27:54