Names
Name
Species
Main
FANCD2 
Homo sapiens 
True 
Keywords
structure-specific DNA binding, chromosome instability, DNA repair, ds break repair, Ig hypermutation, Irradiation induced foci, nuclear foci, ubiquitin, APB, alt, interstrand crosslinks, FA ID2 complex, histone chaperone, replication fork stability, Fanconi Anemia, alternative end-joining, alt telomere pathway
Location
Location
Species
3p25.3-26 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
BRCA1 nuclear dots 
co-localises with Brca 1. Localisation depends on monoubiquitination by FancA/C/F/G 
Interphase 
ALT-associated PML body 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
27 
33 
NLS 
 
1318 
1321 
NLS 
 
Biological Process
GO ID
Term
Links
GO:0006302 
double-strand break repair 
GO:0000724 
double-strand break repair via homologous recombination 
GO:0016447 
somatic recombination of antibody genes 
GO:0048478 
replication fork protection 
GO:0097681 
double-strand break repair via alternative nonhomologous end joining 
GO:0043247 
telomere maintenance in response to DNA damage 
Molecular Function
GO ID
Term
Links
GO:0043566 
structure-specific DNA binding 
GOIDHERE 
histone chaperone 
Other Function
Function
Links
Epithelial cancer 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-04-12 13:41:54 
2005-12-21 14:39:29