Names
Name
Species
Main
brca2 
Homo sapiens 
True 
FANCD1 
 
False 
Keywords
cancer, chromosome instability, homologous recombination, ds break repair, genetic disease, transcription_coupled repair, tumour suppressor, Fanconi Anemia
Location
Location
Species
13q12.3 
Homo sapiens 
Mus musculus 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
repair foci 
 
Interphase 
cleavage midbody 
 
Annotation
Start
End
Domain
Description
434 
437 
NLS 
 
721 
727 
NLS 
 
1002 
1036 
BRCA2 repeat 
rad51 binding 
1212 
1246 
BRCA2 repeat 
 
1421 
1455 
BRCA2 repeat 
 
1517 
1551 
BRCA2 repeat 
 
1664 
1698 
BRCA2 repeat 
 
1837 
1871 
BRCA2 repeat 
 
1971 
2005 
BRCA2 repeat 
 
3266 
3269 
NLS 
 
3311 
3317 
NLS 
 
Biological Process
GO ID
Term
Links
GO:0006281 
DNA repair 
GO:0006302 
double-strand break repair 
GO:0006283 
transcription-coupled nucleotide-excision repair 
GO:0000910 
cytokinesis 
GO:0000019 
regulation of mitotic recombination 
GO:0006357 
regulation of transcription from Pol II promoter 
Molecular Function
GO ID
Term
Links
Other Function
Function
Links
chromosome instability in -/- mice 
Expression
Experiment
Detail
Links
Immunohistochemistry 
rapidly proliferating cell types undergoing differentiation 
Related Genes
Name
Species
Links
History