Names
X
Name
Species
Main
BLM 
Homo sapiens 
True 
RECQ2 
 
False 
RECQL3 
 
False 
Keywords
+
Location
X
Location
Species
15q26.1 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
S - meiosis 
PML/ND10 bodies 
assembles into fraction of PML bodies with rad51 and RP-A 
PubMed:11173860
PubMed:11309417
G2 
PML/ND10 bodies 
assembles into fraction of PML bodies with rad51 and RP-A 
PubMed:11173860
PubMed:11309417
PubMed:15829507
Interphase 
repair foci 
with PML at sites of ssDNA after radiation 
PubMed:11309417
PubMed:15539948
PubMed:15829507
Interphase 
nucleolus 
 
PubMed:11173860
PubMed:11790298
PubMed:15635413
meiosis 
synaptonemal complex 
in prophase, co-localises with RP-A 
Interphase 
telomere 
in ALT cells 
PubMed:12444098
PubMed:15229185
Interphase 
ALT-associated PML body 
in ALT cells 
PubMed:15075340
anaphase - mitosis 
anaphase bridges 
 
PubMed:17599064
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
159 
7.33 
160.6 
 
1417 
Entrez Protein:XP_012436
PubMed:0010647186
OMIM:210900
Uniprot:P54132
158.4 
6.9 
 
 
1416 
Entrez Protein:O88700
PubMed:9808625
Uniprot:O88700
Annotation
X
Start
End
Domain
Description
126 
132 
NLS 
 
664 
865 
DEAD box 
 
868 
874 
NLS 
 
902 
984 
Helicase 
 
1212 
1292 
HRDC 
 
1335 
1351 
NLS BP 
 
672 
873 
DEAD box 
 
876 
882 
NLS 
 
910 
992 
Helicase 
 
1217 
1297 
HRDC 
 
1333 
1350 
NLS BP 
 
Biological Process
X
GO ID
Term
Links
GO:0006310 
DNA recombination 
PubMed:11101838
PubMed:12975363
OMIM:210900
GO:0006281 
DNA repair 
PubMed:11278509
PubMed:11309417
PubMed:10783165
PubMed:11257107
PubMed:14517203
pubmed:18003860
pubmed:18971343
GO:0006261 
DNA-dependent DNA replication 
GO:0007004 
telomerase-dependent telomere maintenance 
PubMed:12444098
GO:0000019 
regulation of mitotic recombination 
PubMed:14685245
GO:0000819 
sister chromatid segregation 
PubMed:17599064
GOIDHERE 
telomere maintenance 
pubmed:19596237
pubmed: 28877996
pubmed:31171703
GO:0007131 
reciprocal meiotic recombination 
pubmed:20308424
GO:0045943 
positive regulation of transcription from RNA polymerase I promoter 
pubmed: 22106380
Molecular Function
X
GO ID
Term
Links
GO:0003678 
DNA helicase activity 
PubMed:7585968
GO:0048476 
Holliday junction resolvase complex 
pubmed:16849422
GO:0044806 
G-quadruplex DNA unwinding 
pubmed:30279242
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
RecQ 
Escherichia coli 
DmBlm 
Drosophila melanogaster 
PubMed:11283371
Entrez Protein:AAD41441
BLM 
Gallus gallus 
PubMed:11313858
xBlm 
Xenopus laevis 
PubMed:11040210
Sgs1 
Saccharomyces cerevisiae 
PubMed:11138010
Rqh1 
Schizosaccharomyces pombe 
History
X
Created On
Last Changed
2001-04-23 11:48:00 
2008-01-02 14:45:14