Names
X
Name
Species
Main
TCOF-1 
Homo sapiens, Mus musculus 
True 
treacle 
Homo sapiens 
False 
Keywords
X
genetic disease, LisH, nucleolus, rRNA transcription, dna damage response, kinetochore, centrosome, spindle orientation, Treacher Collins syndrome
Location
X
Location
Species
HSA5q32-q33.1 
Homo sapiens 
MMU18 
Mus musculus 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nucleolar 
 
PubMed:11790298
PubMed:9811939
PubMed:9736782
pubmed:25064736
Interphase 
actinomycin D 
nucleolar cap 
PubMed:15249688
Interphase 
centrosome 
 
pubmed:22479190
metaphase - mitosis 
kinetochore 
 
pubmed:22479190
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
144.3 
9.06 
 
 
1411 
Entrez Protein:Q13428
PubMed:9736782
OMIM:154500
Uniprot:Q13428
 
 
 
 
1320 
Entrez Protein:NP_035682
PubMed:9158147
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0001510 
RNA methylation 
PubMed:15930015
GO:0006364 
rRNA processing 
PubMed:15930015
GO:0006356 
regulation of transcription from Pol I promoter 
PubMed:15249688
pubmed:19527688
GO:0022008 
neurogenesis 
pubmed:22479190
GO:0007067 
mitosis 
pubmed:22479190
GO:0051294 
establishment of spindle orientation 
pubmed:22479190
GOIDHERE 
DNA damage response, detection of DNA damage 
pubmed:25064736
Molecular Function
X
GO ID
Term
Links
GO:0001042 
RNA polymerase I core binding 
pubmed:19527688
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-04-25 10:06:16 
2005-08-18 14:18:42