Names
Name
Species
Main
TCOF-1 
Homo sapiens, Mus musculus 
True 
treacle 
Homo sapiens 
False 
Keywords
genetic disease, LisH, nucleolus, rRNA transcription, dna damage response, kinetochore, centrosome, spindle orientation, Treacher Collins syndrome
Location
Location
Species
HSA5q32-q33.1 
Homo sapiens 
MMU18 
Mus musculus 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
actinomycin D 
nucleolar cap 
Interphase 
centrosome 
 
metaphase - mitosis 
kinetochore 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
NLS 
 
38 
lisH 
 
61 
78 
NLS BP 
 
907 
1003 
NLS 
 
1049 
1052 
NLS 
 
1194 
1203 
NLS 
 
1270 
1289 
NLS BP 
 
1359 
1405 
NLS BP 
 
Biological Process
GO ID
Term
Links
GO:0001510 
RNA methylation 
GO:0006364 
rRNA processing 
GO:0006356 
regulation of transcription from Pol I promoter 
GO:0022008 
neurogenesis 
GO:0007067 
mitosis 
GO:0051294 
establishment of spindle orientation 
GOIDHERE 
DNA damage response, detection of DNA damage 
Molecular Function
GO ID
Term
Links
GO:0001042 
RNA polymerase I core binding 
Other Function
Function
Links
Expression
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-04-25 10:06:16 
2005-08-18 14:18:42