Names
Keywords
ATM phosphorylation, ds break repair, Irradiation induced foci, nucleolus, PML bodies, ubiquitin ligase, stem cell, Polycomb
Location
Location
Species
12q14.3-q15 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear-cytoplasmic shuttling 
shuttling prevented by p14ARF 
Interphase 
PML/ND10 bodies 
after overexpression of PML 
Interphase 
IR-induced foci 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
181 
185 
NLS 
 
438 
478 
RING finger 
 
Biological Process
GO ID
Term
Links
GO:0006302 
double-strand break repair 
GO:0016574 
histone ubiquitination 
GO:0007049 
cell cycle 
GO:0019827 
stem cell maintenance 
GO:0006340 
negative regulation of transcription of homeotic gene (Polycomb group) 
Molecular Function
GO ID
Term
Links
GO:0004842 
ubiquitin-protein ligase activity 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
MDM2 
Xenopus laevis 
History
Created On
Last Changed
2001-05-02 09:48:35 
2005-05-04 12:57:22