Names
Name
Species
Main
p53 
Homo sapiens 
True 
TP53 
 
False 
LFS1 
 
false 
Keywords
Cajal body, cancer, chromatin remodelling, DNA damage, Irradiation induced foci, nucleolus, nucleotide excision repair, tumour suppressor, ubiquitin, nucleolar cavities, pioneer factor, retrotransposon silencing
Location
Location
Species
17p13.1 
Mus musculus 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear-cytoplasmic shuttling 
shuttles. Accumulates in nucleus after stress. Monoubiquitination leads to nuclear export. 
Interphase 
nucleolar 
In cells treated with MG132 and in nucleolar cavities 
Interphase 
Cajal bodies 
 
Interphase 
PML/ND10 bodies 
interaction with HIPK2 
Interphase 
IR-induced foci 
with gamma H2A.X and ATM 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Biological Process
GO ID
Term
Links
GO:0006915 
apoptosis 
GO:0006338 
chromatin remodeling 
GO:0000122 
negative regulation of transcription from Pol II promoter 
GO:0006289 
nucleotide-excision repair 
GO:0006974 
response to DNA damage stimulus 
GO:0006357 
regulation of transcription from Pol II promoter 
GO:0031937 
positive regulation of chromatin silencing 
Molecular Function
GO ID
Term
Links
GO:0003682 
chromatin binding 
GO:0000981 
sequence-specific DNA binding RNA polymerase II transcription factor activity 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-05-02 10:05:00 
2006-01-31 16:50:19