Names
X
Name
Species
Main
ATP-dependent DNA helicase II 70 kDa subunit 
 
False 
CTC75 
 
False 
CTCBF 
 
False 
G22P1 
 
False 
Ku70 
Gallus gallus, Homo sapiens, Mus musculus 
True 
TLAA 
Homo sapiens 
False 
Keywords
X
autoantigen, chromosome scaffold, DNA repair, DNA_PK, ds break repair, helicase, mitotic chromosomes, nhej, nuclear mRNA splicing via spliceosome, recombination, RNA polymerase II CTD, lyase
Location
X
Location
Species
22q11-q13 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nucleolus 
 
PubMed:11790298
PubMed:12429849
PubMed:1639139
Mitosis 
chromosome surface 
 
PubMed:15609038
PubMed:1639139
Interphase 
nuclear periphery 
 
Interphase 
nuclear speckles 
co-localization with elongating RNA polymerase II 
PubMed:12391174
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
69.8 
6.23 
70 
 
609 
Entrez Protein:P12956
PubMed:11493912
OMIM:152690
genelynxhs:4131
Uniprot:P12956
 
 
 
 
609 
Uniprot:P23475
 
 
 
 
632 
Uniprot:O93257
Annotation
X
Start
End
Domain
Description
308 
454 
ku 
 
542 
545 
NLS 
 
553 
556 
NLS 
 
573 
607 
sap 
 
Biological Process
X
GO ID
Term
Links
GO:0006303 
double-strand break repair via nonhomologous end-joining 
PubMed:15574326
PubMed:9810228
pubmed:20538911
pubmed:20383123
GO:0000398 
nuclear mRNA splicing, via spliceosome 
PubMed:12176931
PubMed:11991638
Molecular Function
X
GO ID
Term
Links
GO:0003677 
DNA binding 
PubMed:11493912
PubMed:11457852
pubmed:20538911
GO:0003678 
DNA helicase activity 
PubMed:9810228
GOIDHERE 
5.-deoxyribose-5-phosphate lyase activity 
pubmed:20383123
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
hdf1 
Saccharomyces cerevisiae 
History
X
Created On
Last Changed
2001-07-04 16:33:22 
2004-12-02 15:09:52