Names
Name
Species
Main
DNA (cytosine-5-)-methyltransferase 3a 
Homo sapiens, Mus musculus 
False 
DNMT3a 
Homo sapiens, Mus musculus 
True 
ES485 
Mus musculus 
False 
Keywords
growth, dna methylase, gene trap, histone deacetylase complex, histone methylation, PWWP domain, mitotic chromosomes, repression complex, transcription repression, methyl-lysine binding, ADD domain, transcription elongation, H3K36me3 binding, genetic disease, acute leukemia, cancer, differentiation, mutated in cancer, AML, Tatton-Brown-Rahman syndrome, overgrowth
Location
Location
Species
12 
Mus musculus 
2p23 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
heterochromatin 
 
Interphase 
nuclear diffuse 
gene -trap is nuclear diffuse. Dnmt3a2 isoform is also diffuse over chromatin 
Mitosis 
chromosomal 
depends on PWWP domain 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Biological Process
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
GO:0006306 
DNA methylation 
GO:0006346 
methylation-dependent chromatin silencing 
GO:0045944 
positive regulation of transcription from RNA polymerase II promoter 
GO:0048863 
stem cell differentiation 
Molecular Function
GO ID
Term
Links
GO:0003886 
DNA (cytosine-5-)-methyltransferase activity 
GO:0035064 
methylated histone residue binding 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-07-05 16:20:38 
2004-12-04 20:37:52