Names
X
Name
Species
Main
hCdc21 
Homo sapiens 
False 
MCM4 
Homo sapiens 
True 
RLF-M 
Homo sapiens 
False 
Keywords
X
AAA, chromatin associated, DNA replication licensing, helicase, replicative helicase, MCM family, replication origin, genetic disease, CMG complex
Location
X
Location
Species
8q12-q13 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
chromatin 
 
PubMed:10722676
Interphase 
replication origins 
 
PubMed:10722676
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
96.6 
6.28 
 
 
863 
Entrez Protein:S65954
Uniprot:P33991
PubMed:22354167
 
 
 
 
862 
Entrez Protein:S56766
Uniprot:P49717
Annotation
X
Start
End
Domain
Description
33 
39 
NLS 
 
267 
770 
MCM 
 
502 
654 
AAA ATPase 
 
795 
798 
NLS 
 
33 
38 
NLS 
 
794 
797 
NLS 
 
Biological Process
X
GO ID
Term
Links
GO:0006275 
regulation of DNA replication 
PubMed:10834843
Molecular Function
X
GO ID
Term
Links
GO:0003678 
DNA helicase activity 
PubMed Central:11136247
GO:0003688 
DNA replication origin binding 
PubMed:10834843
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
MCM4 
Xenopus laevis 
Entrez Protein:T47223
MCM4 
Drosophila melanogaster 
Entrez Protein:S59872
History
X
Created On
Last Changed
2001-07-06 17:33:03 
2002-06-17 10:28:34