Names
Name
Species
Main
EPAS-1 
Homo sapiens, Mus musculus 
True 
HIF-2 alpha 
 
False 
HRF 
Homo sapiens, Mus musculus 
False 
MOP2 
Homo sapiens, Mus musculus 
False 
bHLHe73 
 
false 
PASD2 
 
false 
HIF2A 
 
false 
Keywords
predominantly endothelial cells, transcription factor, hypoxia, HLH, pas domain, genetic disease
Location
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear diffuse 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
14 
30 
NLS BP 
 
20 
75 
HLH 
 
86 
152 
PAS 
 
232 
298 
PAS 
 
304 
347 
PAC 
 
Biological Process
GO ID
Term
Links
GO:0006357 
regulation of transcription from Pol II promoter 
GO:0032364 
oxygen homeostasis 
Molecular Function
GO ID
Term
Links
GO:0003677 
DNA binding 
GO:0003704 
specific RNA polymerase II transcription factor activity 
Other Function
Function
Links
activates transcription of the endothelial tyrosine kinase gene Tie-2 
remodeling of the primary vascular network into a mature hierarchy pattern 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-07-12 12:53:41 
2002-04-12 13:55:26