Names
X
Name
Species
Main
lamin B receptor 
 
False 
LBR 
Gallus gallus, Homo sapiens 
True 
LMN2R 
 
False 
p58 
 
False 
Keywords
X
genetic disease, heterochromatin binding, PxVxL, integral membrane protein, mitotic chromosomes, nuclear periphery, SR_RS domain, inm, histone binding, cholesterol biosynthesis, ER, methylated H4K20 binding, tudor, sterol reductase
Location
X
Location
Species
1q42.1 
Homo sapiens 
1 
Mus musculus 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
inner nuclear membrane 
inner nuclear membrane 
PubMed:9003786
anaphase - mitosis 
chromosome surface 
recruited before emerin and in more peripheral location 
PubMed:10671368
Interphase 
endoplasmic reticulum 
 
pubmed:21327084
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
70.7 
9.41 
 
 
615 
Entrez Protein:NP_919424
PubMed:12118250
PubMed:12490533
PubMed:12618959
OMIM:169400
Uniprot:Q14739
PubMed:9878250
 
 
 
 
637 
Entrez Protein:P23913
Uniprot:P23913
 
 
 
 
626 
Entrez Protein:NP_598576
Annotation
X
Start
End
Domain
Description
4 
62 
tudor 
 
63 
79 
NLS BP 
 
73 
98 
SR/RS 
 
95 
111 
NLS BP 
 
169 
172 
NLS 
 
209 
231 
transmembrane 
psort 
253 
275 
transmembrane 
psort 
296 
318 
transmembrane 
smart only 
322 
344 
transmembrane 
psort 
392 
408 
transmembrane 
psort 
418 
434 
transmembrane 
psort 
451 
467 
transmembrane 
psort 
485 
501 
transmembrane 
psort 
Biological Process
X
GO ID
Term
Links
GO:0006325 
establishment and/or maintenance of chromatin architecture 
PubMed:15882967
PubMed:9169472
GO:0006998 
nuclear membrane organization and biogenesis 
PubMed:12118250
PubMed:14617022
PubMed:9003786
GO:0016126 
cholesterol biosynthetic process 
pubmed:22140257
Molecular Function
X
GO ID
Term
Links
GO:0042393 
histone binding 
pubmed:22052904
GO:0050613 
delta14-sterol reductase activity 
pubmed:22140257
GO:0035064 
methylated histone binding 
pubmed:23100253
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
+