Names
X
Name
Species
Main
DNA-dependent protein kinase catalytic subunit 
 
False 
DNA-PK 
 
False 
DNA-PKCS 
Homo sapiens, Mus musculus 
True 
DNPK1 
 
False 
PRKDC 
 
False 
Keywords
X
ATM, chromosome instability, DNA damage, DNA repair, ds break repair, fat domain, linker histone phosphorylation, nhej, PI3kinase, telomere
Location
X
Location
Species
8q11 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
S - interphase 
nuclear diffuse 
cytoplasmic in G1, moves to nucleus in G1/S 
PubMed:10614713
Interphase 
nucleolus 
 
PubMed:11790298
PubMed:12429849
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
469.1 
6.78 
 
 
4128 
Entrez Protein:P78527
PubMed:15698568
PubMed:95401275
OMIM:600899
Uniprot:P78527
 
 
 
 
4128 
Entrez Protein:P97313
Uniprot:P97313
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006302 
double-strand break repair 
PubMed:10854421
GO:0006303 
double-strand break repair via nonhomologous end-joining 
PubMed:10854421
PubMed:15574326
GO:0016572 
histone phosphorylation 
PubMed:15671175
GO:0007004 
telomerase-dependent telomere maintenance 
PubMed:11340158
PubMed:11742099
GO:0006975 
DNA damage induced protein phosphorylation 
PubMed:15059890
PubMed:15389585
Molecular Function
X
GO ID
Term
Links
GO:0004677 
DNA-dependent protein kinase activity 
PubMed:10854421
Other Function
X
Function
Links
SCID mutation 
PubMed:9398856
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
TOR1 
Saccharomyces cerevisiae 
PubMed:11790298
History
X
Created On
Last Changed
2001-07-16 15:24:25 
2005-04-28 13:03:34