Names
Name
Species
Main
DNA ligase IV 
Homo sapiens 
True 
LIG4 
 
false 
Keywords
brct, chromosome breakage, chromosome instability, ds break repair, genetic disease, immunodeficiency, nhej, microcephaly
Location
Location
Species
13q22-q34 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
 
 
 
 
912 
Annotation
Start
End
Domain
Description
245 
585 
DNA ligase 
 
623 
229 
NLS 
 
632 
638 
NLS 
 
656 
733 
BRCT (breast cancer susceptibility protein signatu 
 
810 
901 
BRCT (breast cancer susceptibility protein signatu 
 
Biological Process
GO ID
Term
Links
GO:0006303 
double-strand break repair via nonhomologous end-joining 
Molecular Function
GO ID
Term
Links
GO:0003910 
DNA ligase (ATP) activity 
GO:0003686 
DNA repair enzyme 
Other Function
Function
Links
late embryonic lethality 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History