Names
Name
Species
Main
PAB2 
Homo sapiens 
True 
PABII 
 
False 
PABP2 
 
False 
PABPN1 
 
False 
OPMD 
 
false 
Keywords
genetic disease, mRNA export, RRM, mRNA 3 processing, nuclear mRNA splicing via spliceosome, polyadenylation factor, translation, sno RNA biogenesis
Location
Location
Species
14q11.2-q13 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
splicing speckles 
inferred from presence in in vitro assembled spliceosomes 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
21 
27 
NLS 
 
173 
245 
RRM 
 
Biological Process
GO ID
Term
Links
GO:0000398 
nuclear mRNA splicing, via spliceosome 
GO:0006380 
poly-A binding 
GO:0055001 
muscle cell development 
GO:0045445 
myoblast differentiation 
GO:0016973 
poly(A)+ mRNA export from nucleus 
GO:0016074 
snoRNA metabolic process 
GO:0006402 
mRNA catabolic process 
Molecular Function
GO ID
Term
Links
GO:0008143 
poly(A) binding 
Other Function
Function
Links
dysphagia and progressive ptosis of the eyelids 
Stimulates muscle-specific gene expression. Interaction with SKIP 
Expression
Related Genes
Name
Species
Links
PAB2 
Saccharomyces cerevisiae 
History
Created On
Last Changed
2001-07-25 11:42:48 
2004-12-02 15:09:52