Names
Name
Species
Main
emerin 
Homo sapiens, Mus musculus, Rattus norvegicus 
True 
Keywords
genetic disease, integral membrane protein, mitotic chromosomes, nuclear periphery, ERK signalling, lem domain
Location
Location
Species
Xq28 
Homo sapiens 
Mus musculus 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
inner nuclear membrane 
relocalised to ER in lamin A- cells 
telophase 
chromosome surface 
reforming nuclear envelope around chromosomes - at "core" regions close to spindle 
Interphase 
inner nuclear membrane 
relocalised to cytoplasm when laminA/C silenced by siRNA in human endometrial cells 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
 
 
 
 
260 
Annotation
Start
End
Domain
Description
45 
lem 
binding to baf 
31 
47 
NLS BP 
 
229 
245 
transmembrane 
 
Biological Process
GO ID
Term
Links
GO:0007517 
muscle development 
GO:0006998 
nuclear membrane organization and biogenesis 
GO:0070372 
negative regulation of ERK1 and ERK2 cascade 
Molecular Function
GO ID
Term
Links
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
emr-1 
Caenorhabditis elegans 
History