Names
Keywords
chromatin associated, inm, integral membrane protein, nuclear matrix, nuclear periphery, transcription repression, hedgehog signalling
Location
Location
Species
12 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear diffuse 
alpha is intra-nuclear (NB has no TM), component of matrix 
Interphase 
inner nuclear membrane 
beta and gamma isoforms are integral membrane proteins 
metaphase - mitosis 
spindle poles 
LAP2 alpha 
Interphase 
chromatin 
lap2 alpha 
anaphase - mitosis 
telomere 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
75.5 
7.19 
 
 
694 
50.7 
9.39 
 
 
454 
Annotation
Start
End
Domain
Description
110 
153 
lem 
 
352 
358 
NLS 
 
110 
153 
lem 
binds BAF 
258 
264 
NLS 
 
410 
430 
transmembrane 
 
Biological Process
GO ID
Term
Links
GO:0016575 
histone deacetylation 
GO:0000122 
negative regulation of transcription from Pol II promoter 
GO:0006998 
nuclear membrane organization and biogenesis 
GO:0007165 
signal transduction downstream of smoothened 
Molecular Function
GO ID
Term
Links
GO:0003676 
nucleic acid binding 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-07-30 09:39:58 
2005-11-02 14:16:42