Names
Name
Species
Main
ENX-1 
Homo sapiens, Mus musculus 
False 
enx1 
 
False 
EZH2 
Homo sapiens, Mus musculus 
True 
Keywords
actin, histone deacetylase complex, histone methylase, homeotic gene regulation, polycomb complex, PRC2, inactive X, linker histone, polycomb group, SANT, transcription repression, set domain, growth, cancer, H3K27 methylation, ubiquitin-dependent protein degradation, genetic disease, protein methylation, Weaver syndrome, overgrowth
Location
Location
Species
7q35-q36 
Homo sapiens 
Mus musculus 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
PcG bodies 
 
Interphase 
chromatin 
with Eed on inactive X in trophoblast stem cells 
Mitosis 
chromosomal 
with Eed on inactive X in trophoblast stem cells 
Interphase 
cytoplasmic 
 
Annotation
Start
End
Domain
Description
12 
33 
NLS BP 
 
159 
250 
SANT (myb-like DNA binding domain 
 
303 
309 
NLS 
 
350 
356 
NLS 
 
428 
476 
SANT (myb-like DNA binding domain 
 
488 
497 
NLS 
 
612 
733 
SET 
 
12 
33 
NLS BP 
 
159 
250 
SANT (myb-like DNA binding domain 
 
303 
309 
NLS 
 
350 
356 
NLS 
 
428 
476 
SANT (myb-like DNA binding domain 
 
488 
497 
NLS 
 
612 
733 
SET 
 
Biological Process
GO ID
Term
Links
GO:0030041 
actin filament polymerization 
GO:0030183 
B-cell differentiation 
GO:0006342 
chromatin silencing 
GO:0009790 
embryonic development 
GO:0030097 
hemopoiesis 
GO:0007517 
muscle development 
GO:0006479 
protein methylation 
GO:0043161 
proteasomal ubiquitin-dependent protein catabolic process 
Molecular Function
GO ID
Term
Links
GO:0046976 
histone lysine N-methyltransferase activity (H3-K27 specific) 
GO:0018024 
histone-lysine N-methyltransferase activity 
GO:0016279 
protein-lysine N-methyltransferase activity 
GO:0016279 
protein-lysine N-methyltransferase activity 
Other Function
Function
Links
Expression
Experiment
Detail
Links
 
declines after birth 
Related Genes
Name
Species
Links
E(Z) 
Drosophila melanogaster 
Set1 
Saccharomyces cerevisiae 
History
Created On
Last Changed
2001-07-31 09:38:59 
2006-01-04 15:07:33