Names
X
Name
Species
Main
ENX-2 
Homo sapiens, Mus musculus 
False 
EZH1 
Homo sapiens, Mus musculus 
True 
Keywords
X
histone methylase, set domain, polycomb group, SANT, H3K27 methylation
Location
X
Location
Species
MMU11 
Mus musculus 
17q21 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
85.3 
8.01 
 
 
747 
Entrez Protein:Q92800
Uniprot:Q92800
85.2 
7.76 
 
 
747 
Entrez Protein:P70351
Uniprot:P70351
Annotation
X
Start
End
Domain
Description
135 
263 
SANT (myb-like DNA binding domain 
 
210 
229 
NLS BP 
 
316 
322 
NLS 
 
360 
365 
NLS 
 
430 
478 
SANT (myb-like DNA binding domain 
 
489 
498 
NLS 
 
613 
734 
SET 
 
135 
263 
SANT (myb-like DNA binding domain 
 
210 
229 
NLS BP 
 
316 
322 
NLS 
 
360 
365 
NLS 
 
430 
478 
SANT (myb-like DNA binding domain 
 
489 
498 
NLS 
 
613 
734 
SET 
 
Biological Process
X
GO ID
Term
Links
GO:0000122 
negative regulation of transcription from RNA polymerase II promoter 
pubmed: 22042701
GO:0016571 
histone methylation 
pubmed: 22042701
GO:0043588 
skin development 
pubmed:21317239
Molecular Function
X
GO ID
Term
Links
GO:0071558 
histone methylase activity (H3-K27 specific) 
pubmed: 22042701
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
 
high in hematopoietic stem cells 
pubmed:hematopoietic stem
 
rises after birth 
pubmed:21317239
Related Genes
X
Name
Species
Links
E(Z) 
Drosophila melanogaster 
PubMed:8921387
Mes2 
Caenorhabditis elegans 
PubMed:12077420
Set1 
Saccharomyces cerevisiae 
curly leaf 
Arabidopsis 
Fis1 
Arabidopsis 
MEA 
Arabidopsis 
EZA1 
Arabidopsis 
History
X
Created On
Last Changed
2001-07-31 10:01:54 
2002-04-12 14:56:48