Names
X
Name
Species
Main
CBX4 
Homo sapiens, Mus musculus 
False 
PC2 
Homo sapiens, Mus musculus 
True 
NBP16 
 
false 
Keywords
+
Location
X
Location
Species
17q25.3 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
PcG bodies 
with CtBP 
PubMed:12679040
PubMed:17428788
PubMed:9858600
Interphase 
heterochromatin 
associated with pericentric heterochromatin on HSA1 
PubMed:17428788
PubMed:9722603
Mitosis 
heterochromatin 
remains associated with pericentric heterochromatin 
PubMed:9722603
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
61.2 
9.47 
 
 
558 
Entrez Protein:NP_003646
Uniprot:O00257
60.6 
9.39 
 
 
551 
Entrez Protein:O55187
Annotation
X
Start
End
Domain
Description
10 
62 
Chromo 
 
290 
310 
NLS BP 
 
322 
329 
NLS 
 
409 
427 
NLS BP 
 
10 
62 
Chromo 
 
292 
312 
NLS BP 
 
325 
331 
NLS 
 
406 
424 
NLS BP 
 
Biological Process
X
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
PubMed:12101246
GO:0000122 
negative regulation of transcription from Pol II promoter 
PubMed:12679040
PubMed:9858600
GO:0019827 
stem cell maintenance 
pubmed: 21885019
pubmed:23362346
GO:2000773 
negative regulation of cellular senescence 
pubmed: 21885019
GO:0048863 
stem cell differentiation 
pubmed:22226355
GOIDHERE 
DNA damage response, detection of DNA damage 
pubmed:22402492
GO:0016925 
protein sumoylation 
pubmed:22402492
pubmed:24434214
GO:0048538 
thymus development 
pubmed:23362346
GO:0030855 
epithelial cell differentiation 
pubmed:26711500
Molecular Function
X
GO ID
Term
Links
GO:0019789 
SUMO ligase activity 
PubMed:12679040
PubMed:17018294
pubmed: 21885019
pubmed:22402492
pubmed:24434214
GO:0032183 
SUMO binding 
pubmed:20176810
GO:0035064 
methylated histone residue binding 
pubmed:21047797
Other Function
X
Function
Links
sumo E3 ligase 
PubMed:12679040
Expression
X
Experiment
Detail
Links
 
highly expressed in the thymic epithelium 
pubmed:23362346
Related Genes
X
Name
Species
Links
Pc 
Drosophila melanogaster 
PubMed:11250141
History
X
Created On
Last Changed
2001-07-31 10:15:08 
2007-06-07 14:47:03