DNA repair, histone deacetylase, myogenesis, transcription repression, Class II HDAC, nuclear & cytoplasmic, genetic disease, BDMR syndrome
Interphase
nuclear-cytoplasmic shuttling
MEF retains it in nucleus.P sends it to cytoplasm. Shuttles in myoblasts. Nuclear in myotubes.
Interphase
repair foci
of DNA damage after ds breaks, together with 53BP1
Interphase
cytoplasmic
in neurons
1059
1066
NES
CRM1-mediated
GO:0016575
histone deacetylation
GO:0000122
negative regulation of transcription from Pol II promoter
GO:0001501
skeletal development
GOIDHERE
neuronal survival
GO:0004407
histone deacetylase activity
HDA1
Saccharomyces cerevisiae
2001-08-07 09:44:40
2004-12-09 10:19:51