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Names
X
Name
Species
Main
HD2
False
HDAC2
Gallus gallus, Homo sapiens, Mus musculus
True
Keywords
X
Class I HDAC, histone deacetylase, polycomb complex, nuclear mRNA splicing via spliceosome, nuclear receptor interacting, nurd, Sin3, transcription repression, pluripotency, chromosome segregation, CdLS, genetic disease
Location
X
Location
Species
6q21
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
S - interphase
replication foci
with DNMT1 in late S
PubMed:10888872
S - interphase
heterochromatin
in late S
PubMed:10888872
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
55.3
5.52
488
Entrez Protein:Q92769
Uniprot:Q92769
PubMed:30806031
55.3
5.59
488
Entrez Protein:P70288
Uniprot:P70288
488
Uniprot:P56519
Annotation
X
Start
End
Domain
Description
10
322
HDAC
Class I
10
322
HDAC
Class I
Biological Process
X
GO ID
Term
Links
GO:0006338
chromatin remodeling
PubMed:10888872
GO:0000122
negative regulation of transcription from Pol II promoter
PubMed:11516394
PubMed:10444591
PubMed:11013263
GO:0000398
nuclear mRNA splicing, via spliceosome
PubMed:12176931
GO:0006340
negative regulation of transcription of homeotic gene (Polycomb group)
pubmed:20075857
GO:0019827
stem cell maintenance
pubmed:24958871
GO:0007059
chromosome segregation
pubmed:24958871
Molecular Function
X
GO ID
Term
Links
GO:0004407
histone deacetylase activity
PubMed:10220385
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
Rpd3
Saccharomyces cerevisiae
History
X
Created On
Last Changed
2001-08-23 15:16:52
2004-12-02 15:09:52