Names
Name
Species
Main
nsd1 
Homo sapiens, Mus musculus 
True 
Keywords
acute leukemia, AML, cancer, genetic disease, histone methylase, set domain, leukaemia, leukaemia_associated translocation, mental retardation, nuclear receptor interacting, PWWP domain, PHD finger, transcription co activator, transcription corepressor, meth, H3K36me3 binding, H3K36 methylation, DNA methylation, Sotos, overgrowth
Location
Location
Species
5q35.3 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
284.1 
8.24 
 
 
2588 
Annotation
Biological Process
GO ID
Term
Links
GO:0016571 
histone methylation 
GO:0006357 
regulation of transcription from Pol II promoter 
GO:0044030 
regulation of DNA methylation 
Molecular Function
GO ID
Term
Links
GO:0046975 
histone lysine N-methyltransferase activity (H3-K36 specific) 
GO:0018024 
histone-lysine N-methyltransferase activity 
GO:0035064 
methylated histone residue binding 
Other Function
Function
Links
essential for early post-implantation development 
haploinsufficiency in Sotos syndrome 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
MES4 
Caenorhabditis elegans 
Set2 
Saccharomyces cerevisiae 
History
Created On
Last Changed
2001-08-29 14:06:40 
2005-08-18 13:24:37