Names
X
Name
Species
Main
FEN-1 
Gallus gallus, Homo sapiens, Mus musculus, Rattus norvegicus 
True 
flap structure-specific endonuclease 1 
 
False 
MF1 
 
False 
FEN1 
 
false 
Keywords
X
base excision repair, DNA repair, endonuclease, DNA replication, okasaki fragment processing, replication fork stability, mutated in cancer, structure-specific nuclease
Location
X
Location
Species
19 
Mus musculus 
11q12 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
42.6 
8.8 
 
 
380 
Entrez Protein:NP_004102
PubMed:21496641
 
 
 
 
380 
Uniprot:Q9JHW7
 
 
 
 
380 
Uniprot:Q90YB0
 
 
 
 
378 
Uniprot:P39749
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006284 
base-excision repair 
PubMed:11440997
PubMed:11687589
GO:0006261 
DNA-dependent DNA replication 
PubMed:11258937
PubMed:14718165
PubMed:9278414
GO:0031297 
replication fork processing 
pubmed:24608430
GOIDHERE 
DNA replication, Okazaki fragment processing 
pubmed:22570407
Molecular Function
X
GO ID
Term
Links
GO:0003684 
damaged DNA binding 
PubMed:11258937
PubMed:14718165
GO:0003686 
DNA repair enzyme 
PubMed:11053418
GO:0004519 
endonuclease activity 
PubMed:11053418
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
RAD2 
Schizosaccharomyces pombe 
PubMed:94277093
Rad27 
Saccharomyces cerevisiae 
PubMed:10545607
Uniprot:P26793
History
X
Created On
Last Changed
2001-08-31 11:28:17 
2002-04-16 10:32:59