Names
Name
Species
Main
ADPRT 
 
False 
PARP 1 
Homo sapiens, Mus musculus 
True 
poly(ADP-ribose) polymerase 
 
False 
PPOL 
 
False 
PARP-1 
 
false 
ARDT1 
 
false 
PARP1 
 
false 
Keywords
Location
Location
Species
1q42 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
S/G2 
centromere 
 
metaphase - mitosis 
centromere 
and neocentromeres 
metaphase - mitosis 
chromosomal 
also on arms 
Interphase 
nucleolus 
 
Interphase 
repair foci 
 
interphase 
nuclear diffuse 
delocalized from nucleolus upon DNA damage 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
93 
ZnF_PARP 
 
113 
203 
ZnF_PARP 
 
207 
224 
NLS BP 
 
287 
466 
BRCT (breast cancer susceptibility protein signatu 
 
797 
1011 
parp 
catalytic domain 
553 
633 
WGR 
 
797 
1007 
PARP 
 
Biological Process
GO ID
Term
Links
GO:0006284 
base-excision repair 
GO:0006281 
DNA repair 
GO:0009048 
dosage compensation, by inactivation of X chromosome 
GO:0006325 
establishment and/or maintenance of chromatin architecture 
GO:0000398 
nuclear mRNA splicing, via spliceosome 
GO:0006508 
proteolysis and peptidolysis 
GO:0045944 
positive regulation of transcription from RNA polymerase II promoter 
GO:0016446 
somatic hypermutation of immunoglobulin genes 
GO:0030576 
Cajal body organization 
GO:0043044 
ATP-dependent chromatin remodeling 
GO:0097681 
double-strand break repair via alternative nonhomologous end joining 
Molecular Function
GO ID
Term
Links
GO:0003686 
DNA repair enzyme 
GO:0003950 
NAD+ ADP-ribosyltransferase activity 
GO:0010843 
promoter binding 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
pme-1 
Caenorhabditis elegans 
History
Created On
Last Changed
2001-08-31 11:47:25 
2007-07-31 11:13:16