Names
Name
Species
Main
PRDM2 
Homo sapiens 
False 
RIZ1 
Homo sapiens, Mus musculus 
True 
Keywords
cancer, histone methylase, set domain, protein methyltransferase, zinc finger C2_H2
Location
Location
Species
Mus musculus 
1p36 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
28 
147 
SET 
 
49 
55 
NLS 
 
63 
66 
NLS 
 
166 
172 
NLS 
 
360 
382 
ZnF_C2H2 
 
390 
412 
ZnF_C2H2 
 
405 
421 
NLS BP 
 
483 
506 
ZnF_C2H2 
 
503 
519 
NLS BP 
 
637 
640 
NLS 
 
880 
884 
NLS 
 
1135 
1157 
ZnF_C2H2 
 
1163 
1186 
ZnF_C2H2 
 
1192 
1215 
ZnF_C2H2 
 
1334 
1354 
ZnF_C2H2 
 
1456 
1476 
ZnF_C2H2 
 
1486 
1493 
NLS 
 
1514 
1517 
NLS 
 
1591 
1594 
NLS 
 
Biological Process
GO ID
Term
Links
GO:0016571 
histone methylation 
GO:0006357 
regulation of transcription from Pol II promoter 
Molecular Function
GO ID
Term
Links
GO:0008276 
protein methyltransferase activity 
GO:0003713 
transcription coactivator activity 
Other Function
Function
Links
high incidence of diffuse large B-cell lymphomas (DLBL) and a broad spectrum of unusual tumors in null mice 
several missense mutations of RIZ1 in human tumor tissues and cell lines; one of these was particularly common in human DLBL tumors. 
Expression
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-09-11 10:37:52 
2005-08-22 14:46:59