Names
Name
Species
Main
MBD2 
Homo sapiens, Mus musculus 
True 
NY-CO-41 
 
False 
Keywords
DNA methylation, histone deacetylase complex, neocentromere, nurd, repression complex, RGG, transcription repression, MBD domain
Location
Location
Species
18 
Mus musculus 
18q21 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
heterochromatin 
 
Mitosis 
pericentric heterochromatin 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Biological Process
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
GO:0006346 
methylation-dependent chromatin silencing 
GO:0000122 
negative regulation of transcription from Pol II promoter 
Molecular Function
GO ID
Term
Links
GO:0003677 
DNA binding 
GO:0003723 
RNA binding 
Other Function
Function
Links
-/- mice are viable and fertile. Maternal behavior of Mbd2-/- mice is however defective 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-09-21 18:12:57 
2004-09-13 17:24:46