Names
X
Name
Species
Main
NRSF 
 
False 
REST 
Homo sapiens 
True 
Keywords
X
deacetylase complex, neural development, histone deacetylase complex, histone methylation, spindle checkpoint, Sin3, transcription repression, zinc finger C2_H2, polycomb recruitment
Location
X
Location
Species
4q12-q13.3 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nuclear 
 
PubMed:12881722
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
121.9 
6.3 
 
 
1097 
Entrez Protein:NP_005603
genelynxhs:648
Annotation
X
Start
End
Domain
Description
159 
181 
ZnF_C2H2 
 
216 
238 
ZnF_C2H2 
 
248 
270 
ZnF_C2H2 
 
276 
298 
ZnF_C2H2 
 
304 
326 
ZnF_C2H2 
 
332 
355 
ZnF_C2H2 
 
361 
383 
ZnF_C2H2 
 
389 
412 
ZnF_C2H2 
 
542 
546 
NLS 
 
569 
586 
NLS BP 
 
814 
833 
NLS BP 
 
1060 
1082 
ZnF_C2H2 
 
Biological Process
X
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
PubMed:12399542
PubMed:15200951
PubMed:16288918
GO:0000122 
negative regulation of transcription from Pol II promoter 
PubMed:11516394
PubMed:10688661
PubMed:12399542
PubMed:15907476
pubmed:19201947
pubmed:19561591
GO:0042055 
neuronal lineage restriction 
PubMed:15907476
pubmed:22791895
GO:0031577 
spindle checkpoint 
pubmed:18354482
GO:0019827 
stem cell maintenance 
pubmed:18362916
pubmed:18959480
pubmed:22791895
GOIDHERE 
neural development 
pubmed:22791895
GO:0045888 
regulation of transcription of homeotic gene (Polycomb group) 
pubmed:22964890
pubmed:22396653
Molecular Function
X
GO ID
Term
Links
GO:0003677 
DNA binding 
PubMed:11145971
PubMed:12399542
Other Function
X
Function
Links
embryonic lethality -/- 
PubMed:10688661
Expression
+
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-10-05 15:37:33 
2005-08-22 14:46:09