Names
Name
Species
Main
NF-E2p45 
Homo sapiens 
True 
Keywords
haemopoiesis, heterodimer, leucine zipper, transcription factor
Location
Location
Species
12q13 
Homo sapiens 
15 
Mus musculus 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear diffuse 
in both undifferentiated and differentiated MEL cells 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
264 
328 
BRLZ 
 
271 
288 
NLS BP 
 
Biological Process
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
GO:0006357 
regulation of transcription from Pol II promoter 
Molecular Function
GO ID
Term
Links
GO:0003704 
specific RNA polymerase II transcription factor activity 
Other Function
Function
Links
essential factor for megakaryocyte maturation and platelet production. Neonates exhibit severe anemia and dysmorphic red cell changes,but surviving adults globin chain synthesis was balanced, and switching from fetal to adult globins progressed normally. 
Expression
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-10-12 12:01:11 
2003-11-07 10:10:06