methylated H4K20 binding, ds break repair, brct, DNA damage, Ig class switching, Irradiation induced foci, transcription co activator, nhej, ubiquitinated H2A binding, inhibition of end resection, checkpoint, repair foci, opt domain, tudor, mitotic clock
Interphase
nuclear diffuse
Interphase
IR-induced foci
after irradiation to induce ds breaks. Co-localisation to mre11/rad50 foci. Requires H2A.X
prophase - mitosis
kinetochore
co-localisation with CENP-E
metaphase - mitosis
kinetochore
released by mid anaphase
GO:0006357
regulation of transcription from Pol II promoter
GO:0016447
somatic recombination of antibody genes
GO:0006303
double-strand break repair via nonhomologous end joining
GO:0072421
detection of DNA damage stimulus involved in DNA damage checkpoint
GO:2001034
positive regulation of double-strand break repair via nonhomologous end joining
GO:0003682
chromatin binding
GO:0035064
methylated histone residue binding
GO:0061649
ubiquitinated histone binding
Rad9
Saccharomyces cerevisiae
crb2
Schizosaccharomyces pombe
2001-10-12 17:14:47
2005-04-26 13:48:40