Names
Name
Species
Main
53BP1 
Homo sapiens 
True 
TP53BP1 
 
false 
p202 
 
false 
Keywords
Location
Location
Species
15q15-q21 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear diffuse 
 
Interphase 
IR-induced foci 
after irradiation to induce ds breaks. Co-localisation to mre11/rad50 foci. Requires H2A.X 
prophase - mitosis 
kinetochore 
co-localisation with CENP-E 
metaphase - mitosis 
kinetochore 
released by mid anaphase 
Interphase 
repair foci 
 
Interphase 
OPT domain 
 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
1395 
1401 
NLS 
 
1483 
1540 
tudor 
threshold 
1626 
1630 
NLS 
 
1661 
1838 
BRCT (breast cancer susceptibility protein signatu 
 
1668 
1685 
NLS BP 
 
1866 
1954 
BRCT (breast cancer susceptibility protein signatu 
 
Biological Process
GO ID
Term
Links
GO:0006281 
DNA repair 
GO:0006357 
regulation of transcription from Pol II promoter 
GO:0016447 
somatic recombination of antibody genes 
GO:0006303 
double-strand break repair via nonhomologous end joining 
GO:0072421 
detection of DNA damage stimulus involved in DNA damage checkpoint 
GO:2001034 
positive regulation of double-strand break repair via nonhomologous end joining 
GOIDHERE 
mitosis 
Molecular Function
GO ID
Term
Links
GO:0003682 
chromatin binding 
GO:0035064 
methylated histone residue binding 
GO:0061649 
ubiquitinated histone binding 
Other Function
Function
Links
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
Rad9 
Saccharomyces cerevisiae 
crb2 
Schizosaccharomyces pombe 
History
Created On
Last Changed
2001-10-12 17:14:47 
2005-04-26 13:48:40