Names
Name
Species
Main
C/EBP alpha 
Homo sapiens 
True 
CCAAT/enhancer binding protein alpha 
 
False 
CEBPA 
 
False 
Keywords
AML, cell cycle, differentiation, heterodimer, homodimer, leucine zipper, transcription factor, tumour suppressor
Location
Location
Species
19q13.1 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
274 
303 
NLS BP 
 
279 
343 
BRLZ 
 
Biological Process
GO ID
Term
Links
GO:0008285 
negative regulation of cell proliferation 
GO:0000122 
negative regulation of transcription from Pol II promoter 
GO:0006357 
regulation of transcription from Pol II promoter 
Molecular Function
GO ID
Term
Links
GO:0003677 
DNA binding 
GO:0003702 
RNA polymerase II transcription factor activity 
Other Function
Function
Links
-/- mice do not store hepatic glycogen. Hepatocytes and adipocytes fail to accumulate lipid. Critical for the establishment and maintenance of energy homeostasis in neonates 
Die shortly after birth. Severely disturbed liver architecture. Impaired accumulation of glycogen and lipids in the liver and adipose tissue. Hypoglycaemic. Role in terminal differentiation hepatocytes. 
Expression
Experiment
Detail
Links
Immunohistochemistry 
fully differentiated cells of liver, gut, adipose, skin, mammary gland 
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-11-13 09:31:27 
2001-11-13 09:59:52