Names
Keywords
histone deacetylase complex, human, myogenesis, transcription corepressor
Location
Location
Species
7p15-p21 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear-cytoplasmic shuttling 
P leads to binding to 14-3-3 and nuclear export 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
65.9 
8.86 
 
 
590 
 
 
 
 
588 
 
 
 
 
1011 
Annotation
Start
End
Domain
Description
117 
120 
NLS 
 
241 
247 
NLS 
 
Biological Process
GO ID
Term
Links
GO:0000122 
negative regulation of transcription from Pol II promoter 
Molecular Function
GO ID
Term
Links
Other Function
Function
Links
inhibitor of myogenesis. Ser phosphorylation by myogenic factors stimulates binding to 14-3-3 and disrupts MEF2 interaction. Moved out of nucleus 
Expression
Experiment
Detail
Links
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-11-15 15:22:42 
2002-04-15 09:49:37