Names
X
Name
Species
Main
H-Y 
 
False 
HYA 
 
False 
JARID1C 
 
False 
SMCX 
Homo sapiens 
True 
XE169 
 
False 
KDM5C 
 
false 
Keywords
X
cancer, ARID_BRIGHT, genetic disease, mental retardation, zinc finger C5HC2, jumonji domain, histone demethylation, H3K4 demethylation, Cleas-Jensen syndrome, microcephaly
Location
X
Location
Species
Xp11.2-11.22 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
175.8 
5.46 
 
 
1560 
Entrez Protein:P41229
PubMed:15586325
OMIM:314690
Uniprot:P41229
PubMed:18203167
PubMed:18697827
PubMed:20054297
 
 
 
 
1554 
Entrez Protein:P41230
Uniprot:P41230
Annotation
X
Start
End
Domain
Description
13 
54 
JmjN 
 
80 
170 
Arid/bright 
 
326 
372 
PHD finger 
 
468 
634 
JmjC 
 
707 
760 
ZnF C5HC2 
 
1187 
1284 
PHD finger 
 
Biological Process
X
GO ID
Term
Links
GO:0016577 
histone demethylation 
PubMed:17320160
PubMed:17468742
GO:0000122 
negative regulation of transcription from Pol II promoter 
PubMed:17468742
Molecular Function
X
GO ID
Term
Links
GO:0032453 
histone demethylase activity (H3-K4 specific) 
pubmed:17320160
pubmed:27058665
Other Function
X
Function
Links
mutated in renal carcinoma 
pubmed:20054297
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-11-28 15:34:56 
2007-09-28 15:21:49