Names
Name
Species
Main
DNA polymerase epsilon 
Homo sapiens 
True 
POLE 
 
False 
POLE1 
 
false 
Keywords
DNA polymerase, DNA repair, leading strand synthesis, genetic disease, cancer, heterotetramer, exonuclease
Location
Location
Species
12q24.3 
Homo sapiens 
Mus musculus 
Subcellular Localisation
Stage
Description
Details
Links
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
172 
178 
NLS 
 
267 
870 
POLBc 
 
764 
780 
NLS BP 
 
884 
887 
NLS 
 
1226 
1233 
NLS 
 
1275 
1292 
NLS BP 
 
1876 
1879 
NLS 
 
2024 
2030 
NLS 
 
Biological Process
GO ID
Term
Links
GO:0006261 
DNA-dependent DNA replication 
GO:1903460 
mitotic DNA replication leading strand elongation 
Molecular Function
GO ID
Term
Links
GO:0003893 
epsilon DNA polymerase activity 
Other Function
Function
Links
Expression
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-12-17 18:31:28 
2001-12-17 18:50:28