Names
X
Name
Species
Main
CCCTC-binding factor 
 
False 
CTCF 
Homo sapiens, Mus musculus, Rattus norvegicus 
True 
Keywords
X
imprinting, cohesion, sumoylated, polycomb bodies, centrosome, dosage compensation by inactivation of X chromosome, insulation, X inactivation, zinc finger C2_H2, genetic disease, mental retardation, microcephaly
Location
X
Location
Species
16q21-q22.3 
Homo sapiens 
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase 
nuclear 
nuclear matrix 
PubMed:12878173
metaphase - mitosis 
centrosome 
 
PubMed:14980504
anaphase - mitosis 
centrosome 
 
PubMed:14980504
telophase 
cleavage midbody 
 
PubMed:14980504
Interphase 
nucleolus 
 
PubMed:16595548
Interphase 
PcG bodies 
when sumoylated 
pubmed:19029252
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
82.8 
6.51 
 
 
727 
Entrez Protein:NP_006556
OMIM:604167
Uniprot:P49711
PubMed:23746550
 
 
 
 
736 
Entrez Protein:NP_851839
 
 
 
 
737 
Entrez Protein:NP_114012
Annotation
+
Biological Process
X
GO ID
Term
Links
GO:0006341 
chromatin insulator sequence binding 
PubMed:10458613
PubMed:11997516
PubMed:12861010
PubMed:14716017
PubMed:15361875
pubmed:20966046
GO:0006338 
chromatin remodeling 
PubMed:14716017
PubMed:16949368
GO:0009048 
dosage compensation, by inactivation of X chromosome 
PubMed:11743158
PubMed:15731119
GO:0006325 
establishment and/or maintenance of chromatin architecture 
PubMed:16951251
pubmed:20478995
GO:0006349 
imprinting 
PubMed:10839546
PubMed:10839547
PubMed:12461525
PubMed:12629040
GO:0000122 
negative regulation of transcription from Pol II promoter 
PubMed:15304340
pubmed:25135475
GO:0007062 
sister chromatid cohesion 
pubmed:18550811
Molecular Function
X
GO ID
Term
Links
GO:0003677 
DNA binding 
PubMed:11743158
PubMed:17382889
PubMed:8649389
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
X
Created On
Last Changed
2001-12-21 11:19:43 
2007-07-30 12:46:04