Names
Name
Species
Main
CCCTC-binding factor 
 
False 
CTCF 
Homo sapiens, Mus musculus, Rattus norvegicus 
True 
Keywords
imprinting, cohesion, sumoylated, polycomb bodies, centrosome, dosage compensation by inactivation of X chromosome, insulation, X inactivation, zinc finger C2_H2, genetic disease, mental retardation, microcephaly
Location
Location
Species
16q21-q22.3 
Homo sapiens 
Subcellular Localisation
Stage
Description
Details
Links
Interphase 
nuclear 
nuclear matrix 
metaphase - mitosis 
centrosome 
 
anaphase - mitosis 
centrosome 
 
telophase 
cleavage midbody 
 
Interphase 
nucleolus 
 
Interphase 
PcG bodies 
when sumoylated 
Protein Sequence
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
Annotation
Start
End
Domain
Description
199 
206 
NLS 
 
254 
260 
NLS 
 
266 
288 
ZnF_C2H2 
 
294 
316 
ZnF_C2H2 
 
322 
345 
ZnF_C2H2 
 
351 
373 
ZnF_C2H2 
 
379 
401 
ZnF_C2H2 
 
407 
430 
ZnF_C2H2 
 
437 
460 
ZnF_C2H2 
 
467 
489 
ZnF_C2H2 
 
495 
517 
ZnF_C2H2 
 
523 
546 
ZnF_C2H2 
 
555 
575 
ZnF_C2H2 
 
598 
601 
NLS 
 
645 
653 
NLS 
 
Biological Process
GO ID
Term
Links
GO:0006338 
chromatin remodeling 
GO:0009048 
dosage compensation, by inactivation of X chromosome 
GO:0006325 
establishment and/or maintenance of chromatin architecture 
GO:0000122 
negative regulation of transcription from Pol II promoter 
GO:0007062 
sister chromatid cohesion 
Molecular Function
GO ID
Term
Links
Other Function
Function
Links
Expression
Related Genes
Name
Species
Links
History
Created On
Last Changed
2001-12-21 11:19:43 
2007-07-30 12:46:04