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FAQs
Names
X
Name
Species
Main
ESET
Mus musculus
False
H3-K9-HMTase 4
False
KIAA0067
Homo sapiens
False
SETDB1
Homo sapiens, Mus musculus
True
KMT1E
false
Keywords
+
Location
X
Location
Species
1q21.2
Homo sapiens
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
PML/ND10 bodies
pubmed:19811652
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
143.2
5.74
1291
Entrez Protein:NP_036564
OMIM:604396
Uniprot:Q15047
144.5
5.71
180
1307
Entrez Protein:NP_061365
Uniprot:O88974
Annotation
X
Start
End
Domain
Description
226
232
NLS
256
318
tudor
346
401
tudor
597
672
MBD
679
786
preSET
802
1272
SET
1275
1291
post SET
256
318
tudor
346
401
tudor
614
689
MBD
696
803
preSET
820
1228
SET
1291
1307
post SET
Biological Process
X
GO ID
Term
Links
GO:0006342
chromatin silencing
PubMed:12398767
PubMed:11959841
pubmed:19884255
pubmed:20164836
pubmed:21427230
GO:0016571
histone methylation
PubMed:11791185
pubmed:19811652
GO:0000122
negative regulation of transcription from RNA polymerase II promoter
pubmed:19884257
pubmed:19811652
GO:0019827
stem cell maintenance
pubmed:19884257
pubmed: 20014010
pubmed:19811652
GO:0007128
meiotic prophase I
pubmed:30393076
Molecular Function
X
GO ID
Term
Links
GO:0046974
histone lysine N-methyltransferase activity (H3-K9 specific)
PubMed:11791185
pubmed:19811652
Other Function
X
Function
Links
peri-implantation lethality between 3.5 and 5.5 dpc. No Eset(-/-) ES cell lines
PubMed:14993285
Expression
+
Related Genes
X
Name
Species
Links
YNCA
Caenorhabditis elegans
Su(var)3-9
Drosophila melanogaster
History
X
Created On
Last Changed
2002-01-17 12:45:31
2005-08-18 13:20:20